摘要
目的 探讨用L 丙氨酰 L 谷氨酰胺强化的肠外营养对外科危重患者营养支持的应用价值。方法 将 2 4例外科危重患者随机分为两组 ,对照组单纯给予静脉营养 ,强化组除给予静脉营养外 ,按 1 5ml/kg补充L 丙氨酰 L 谷氨酰胺。分别在静脉营养治疗的前 1d、治疗后第 4、 7、 14d测定氮平衡、营养指标、免疫功能指标和患者耐受性指标。结果 治疗 7d后两组患者均由负氮平衡转为正氮平衡 ,营养指标、免疫功能指标均明显增高 ,但强化组增高更明显 ;患者耐受性指标中 ,强化组无显著变化 ,对照组则出现血葡萄糖和总胆红素升高。结论 用L 丙氨酰 L 谷氨酰胺强化比单纯的肠外营养更能明显改善危重患者的营养状况和免疫功能 。
Objective To evaluate the effects of L alanyl L glutamine (LALG)intensified parenteral nutrition support in critically ill surgical patients.Methods 24 patients were randomized into two groups:control group received only parenteral nutrition support,LALG group received parenteral nutrition support and LALG(1 5 ml/kg).Nitrogen balance,nutrition,immune functions and patient tolerance parameters were determined at pre treatment and 4th,7th,14th days after treatment.Results After 7 days treatment,the two groups all turned from negative nitrogen balance to positive nitrogen balance.The nutrition and immune functions parameters increased significantly in both groups but more in LALG group.For tolerance parameters,blood glucose and total bilirubin increased obviously in control group with no change in LALG group.Conclusion LALG intensified parenteral nutrition has better effects on improvementof the patients nutrition and immune functions,and patients tolerance is better compared with parenteral nutrition alone. [
出处
《中华急诊医学杂志》
CAS
CSCD
2003年第4期255-257,共3页
Chinese Journal of Emergency Medicine
