摘要
目的 探讨C 反应蛋白 (CRP)对老年感染性疾病诊断价值。方法 对 1 4 2例感染性疾病和 2 1 6例非感染疾病老年患者 ,测定血清C 反应蛋白。以CRP 7～ 2 0mg L、2 1～40mg L和 41～60mg L分层 ,计算诊断试验评价指标。结果 各种感染性疾病老年患者CRP平均水平 (30 .1± 2 .8～69.3± 35.6)mg L ,明显高于对照组 (5 .2± 2 .9)mg L。分层分析显示CRP诊断感染性疾病特异度为83 .3 %～ 99.0 % ,阳性似然比为 3.6、2 7.0和 1 2 8.0。
Objective To evaluate the value of C reactive protein (CRP) to diagnostic test in elderly patients with infections. Methods C reactive protein were investigated in 142 elderly patients with infections and 216 elderly patients without. CRP 7 20,21 40 and 41 60 mg/L were stratified, the index of diagnostic test counted. Results Concentrations of CRP in patients with different diseases were upper respiratory tract infection 36.9 mg/L± 28.9 mg/L , acute bronchitis 30.1 mg/L± 28.1 mg/L, pneumonia 55.9 mg/L± 32.9 mg/L , urinary infection 49.0 mg/L± 27.6 mg/L and enteritis 39.3 mg/L± 35.6 mg/L . They were all higher than those in control group ( 5.2 mg/L± 2.9 mg/L , P < 0.001 ). Stratified analysis disclosed that the specificity of CRP was 83.3% 99.0 % for diagnostic infection disease. The positive likelihood ratio(LR) of 7 20, 21 40 and 41 60 mg/L were 3.6 , 27.0 and 128.0 , respectively.Conclusion C reactive protein was an important marker to diagnose elderly patients with infections.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2003年第4期304-306,共3页
Chinese Journal of Epidemiology
