摘要
目的 了解淋病奈瑟菌的耐药性及β -内酰胺酶的产生情况。方法 对门诊 1998～ 2 0 0 1年分离的 60 2株淋病奈瑟菌进行 14种抗菌药物的耐药性分析 ,同时检测β -内酰胺酶。结果 药敏试验结果显示 :头孢噻肟 (Cefo taxime,CTX)和原始霉素 (Pristinomycin ,PRI)的耐药率分别为 4 65 %和 4 98% ,而甲氧苄氨嘧啶 (Trimethoprim ,TMP)的耐药率为 94 5 2 %。 60 2株淋病奈瑟菌中产β-内酰胺酶淋病奈瑟菌 (PPNG)占 3 8 87% ,抗四环素淋病奈瑟菌 (TRNG)占 16 44 %。
Objective To survey drug resistance and β-lactamase producing.Methods β-lactamase producing Ngonorrhoeae(PPNG) and the drug resistance of 14 antibiotics to 602 strains from 1998 to 2001 were determined respectively.Results The results showed the susceptibility of the isolates to cefotaxime and pristinomycin was highest(9535%,9502% respectively) and trimethoprim was lowest(316%).The drug resistance to trimethoprim was highest(9452%)and cefotaxime and pristinomycin was lowest(465%,498% respectively).3887% of 602 isolates NGonorrhoeae were PPNG,and 1644% were TRNG.Conclusion Cefotaxime and pristinomycin are drugs of first choice in treatment of Neisseria gonorrhoeae infection in this area.
出处
《中国全科医学》
CAS
CSCD
2003年第3期200-202,共3页
Chinese General Practice
关键词
淋病奈瑟菌
耐药性
Β-内酰胺酶
Neisseria gonorrhoeae Drug resistance β-lactamase producing neisseria gonorrhoeae
