摘要
目的:观察健脾益气法对营养性肥胖大鼠体重、Lee指数、胰岛素敏感指数、脂肪组织中肿瘤坏死因子-α(TNF-α)水平的影响。方法:将40只体重50g左右的SD大鼠随机分为4组,即正常组、模型组、中药组、西药组,除正常组外均采用高能量、高脂肪饲料,实验4周造模成功后,治疗组开始药物治疗,实验8周后检测大鼠的上述指标。结果:中药组体重、Lee指数、血糖、血清胰岛素、脂肪组织中TNF-α水平均较模型组有不同程度的降低,胰岛素敏感指数有所提高。结论:健脾益气法可以改善营养性肥胖大鼠糖代谢紊乱状态。
Objective: To investigate the effect of nourishing Qi therapy on weight, Lee-index, insulin resistance and TNF-α concentration of diet-induced obes rats. Methods: 40 SD rats in 21-day old were divided into 4 groups. After induced obesity, they were treated by different ways. At the end, different indexes were tested. Results: Compared with model group, weight, Lee-index, insulin concentration in serum and TNF-αconcentration in fat tissues of NQ group were decreased differently, insulin sensitivity index were increased. Conclusion: The nourishing Qi therapy can improve the sugar metabolism disorder in diet-induced obes rats.
出处
《中国中医药信息杂志》
CAS
CSCD
2003年第2期32-33,共2页
Chinese Journal of Information on Traditional Chinese Medicine
