1Remuzzi G, Bertani T. Pathophysiology of progressive nephropathies. N Engl J Med,1998,339:1 448
2Remuzzi G, Ruggenenti P, Benigni A. Understanding the nature of renal disease progression. Kidney Int, 1997,51:2
3Ruggenenti P, Perna A, Mosconi L et al. Urinary protein excretion rate is the best independent predictor of ESRF in non-diabetic proteinuric chronic nephropathies. Kidney Int, 1998,53:1 209
4Jafar TH, Stark PC, Schmid CH et al. Proteinuria as a modifiable risk factor for the progression of non-diabetic renal diseases. Kidney Int,2001,60:1 131
5Burton C, Harris KP. The role of proteinuria in the progression of chronic renal failure. Am J Kidney Dis,1996,27:765
6Arovin BH, Tan LC. LDL stimulates messangial fibronectin production and chemoattractant expression. Kidney Int, 1993,43:218
7Burton CJ, Harper SJ, Bailey E et al. Turnover of human tubular cells exposed to proteins in vivo and in vitro. Kidney Int,2001,59:507
8Abbate M, Zoja C, Coma D et al. In progressive nephropathies, overload of tubular cells with filtered proteins translates glomerular permeability dysfunction into cellular signals of interstitial inflammation. J Am Soc Nephrol, 1998,9:1 213
9Eddy A. Role of cellular infiltrates in response to proteinuria. Am J Kidney Dis,2001,37(Suppl 2) :S25
10Zoja Z, Donadelli R, Colleoni S et al. Protein overload stimulates RANTES production by proximal tubular cells depending on NF-KB activation. Kidney Int, 1998,53:1 608
