摘要
目的 探讨胃肠道癌手术切除后腹腔及肝转移的防治方法。方法 将 2 82例胃肠道癌切除术后患者分成术中腹腔温热低渗灌洗化疗加术后动脉灌注化疗组 1 69例 (治疗组 )和单纯术后静脉化疗组 1 1 3例 (对照组 ) ,对比两组局部复发率、肝转移率及 3年生存率。结果 治疗组腹腔转移率、肝脏转移率、和 3年生存率依次为 2 1 .9% ,1 2 .4 %和 74.6 % ;对照组依次为 46 .0 % ,2 7.4 %和 46 .8%(均P <0 .0 5)。结论 术中温热低渗灌洗化疗及术后动脉灌注化疗对进展期胃肠道肿瘤术后腹腔复发和肝转移有良好的防治作用。
Objective To study the prevention and treatment of the local and hepatic recurrence after advanced gastrointestal(G1) carcinoma operation.Methods 282 patients were divided into treatment group and control group.The treatment group (hyperthemic peritoneal perfusion plus intraarterial infusion chemotherapy)had 169 patients.The control group (systemic chemtherapy)had 113 patients. The peritoneal and hepatic recurrence and 3 year survival rate were compared between the 2 groups.Results The local and hepatic recurrence and 3 year survival rate in the treatment group were 21.9%,12.4% and 74.6%;those in the control group were 46.0%,27.4% and 46.8%,respectively ( P<0.05).Conculusions Hyperthermic peritoneal perfusion and intraarterial infusion chemotherapy is an effective way to control the local recurrence and hepatic metastasis after advanced G1 neoplasms operation.
出处
《中国普通外科杂志》
CAS
CSCD
2003年第1期25-27,共3页
China Journal of General Surgery
关键词
胃肠肿瘤/药物疗法
腺癌/药物疗法
腹膜灌洗法
灌注
局部
GASTROINTESTINAL NEOPLASMS/drug ther
ADENOCARCINOMA/drug ther
PERITONEAL LAVAGE
FERFUSION,REGIONAL
