期刊文献+

高密度脂蛋白及其受体的研究进展 被引量:6

暂未订购
导出
摘要 本文对高密度脂蛋白的结构组成、代谢、与动脉粥样硬化的关系以及高密度脂蛋白受体的确认过程、与动脉粥样硬化的关系作了综述。小鼠清道夫受体BⅠ被确认是真正介导细胞与高密度脂蛋白作用的受体 ,对于了解高密度脂蛋白胆固醇的代谢是非常有意义的 ,它有可能作为一个新的治疗靶点 ,由此找到预防和治疗动脉粥样硬化性心脑血管疾病的方法。
作者 田德峰 洪斌
出处 《国外医学(药学分册)》 2003年第1期1-5,共5页 Foreign Medical Sciences(Section of Pharmarcy)
基金 国家自然科学基金资助重点项目 (3 993 0 190 )
  • 相关文献

参考文献16

  • 1Garver WS, Deeg MA, Bowen RF, et al. Phosphoproteins regulated by the interaction of high-density lipoprotein with human skin fibroblasts[J]. Atheroscler Thromb Vasc Biol,1997, 17(11) :2698 - 2706.
  • 2Reaven E, Zhan L, Nomoto A, et al. Expression and microvillar localization of scavenger receptor class B, type Ⅰ (SR-B Ⅰ ) and selective cholesteryl ester uptake in Leydig cells from rat testis[J]. J Lipid Res, 2000, 41(3):343-356.
  • 3Brooks-Wilson A, Marcil M, Clee SM, et al. Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency[J]. Nat Genet, 1999, 22(4):336- 345.
  • 4Silver DL, Tall AR. The cellular biology of scavenger receptor class B type Ⅰ [J]. Curr Opin Lipidol, 2001, 12(5):497-504.
  • 5Krieger M. Charting the fate of the"good cholesterrol":identification and characterization of the high-density lipoprotein receptor SR-B Ⅰ [ J ]. Annu Rev Biochem,1999, 68:523- 558.
  • 6Fidge NH. High density lipoprotein receptors, binding proteins, and ligands[J]. J Lipid Res, 1999, 40(2): 187 -201.
  • 7WebbNR, ConnellPM, GrafGA, et al. SR-BⅡ, anisoform of the scavenger receptor B Ⅰ containing an alternate cytoplasmic tail, mediates lipid transfer between high density lipoprotein and cells[J]. J Biol Chem, 1998, 273(24):15241 - 15248.
  • 8Murao K, Terpstra V, GreenSR, et al. Characterization of CLA-1, a human homlogue of rodent scavenger receptor B Ⅰ , as a receptor for high density lipoprotein and apoptotic thymocytes[J]. J Biol Chem, 1997, 272(28): 17551 -17557.
  • 9Rigotti A, Trigatti BL, Penman M, et al. A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type Ⅰ reveals its key role in HDL metabolism [ J ]. Proc Natl Acad Sci USA, 1997, 94(23):12610- 12615.
  • 10Temel RE, Trigatti B, DeMattos RB, et al. Scavenger receptor class B, type Ⅰ (SR-BⅠ) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells[J]. Proc Natl Acad Sci USA, 1997, 94(25): 13600 -13605.

同被引文献73

引证文献6

二级引证文献28

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部