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大鼠肺巨噬细胞内毒素耐受性与TLR4 mRNA表达的变化 被引量：5

Tolerance of lipopolysaccharide related to the expression changes of TLR4 mRNA
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作者 张德明 李永旺 毛宝龄 钱桂生
机构地区 第三军医大学附属新桥医院全军呼吸内科研究所
出处 《第三军医大学学报》 CAS CSCD 北大核心 2003年第5期380-380,384,共2页 Journal of Third Military Medical University
基金 国家自然科学基金资助重点项目 ( 39730 2 10 )
关键词 巨噬细胞 内毒素 耐受性 TLR4mRNA表达 急性肺损伤
分类号 R563.1 [医药卫生—呼吸系统]
  • 相关文献

参考文献8

  • 1Qureshi S T;Lariviere L;Leveque G.Endotoxin-tolerance mice have mutation in Toll-like receptor 4(TLR4)[J],1999(04).
  • 2Arbour N C;Lorenz E;Schutte B C.TLR4 mutations are associated with endotoxin hyporesponsiveness in humans[J],2000(02).
  • 3Medvedev A E;Henneke P;Schromm A.Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4[J],2001(04).
  • 4Wang MJ;Jeng K C G;Shih P C.Differential expression and regulation of marophage inflammatory protein(MIP)-1α and MIP-2 gene by alveolar and peritoneal macrophages in LPS-hyporesponsive C3H/HeJ mice[J],2000.
  • 5Li LW;Cousart S;Hu J.Characteriztion of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells[J],2000(30).
  • 6Aderem A;Ulevitch R J.Toll-like receptors in the induction of the innate immune response[J],2000(17).
  • 7SU G L;Klein R D;Aminlari A.Kupffer cell activation by lipopolysaccharide in rats:role for lipopolysacccharide binding protein and Toll-like receptor 4[J],2000(04).
  • 8Yang H;Young DW;Gusovsky F.Cellular events mediated by lipopolysaccharide-stimulated Toll-like receptor 4[J],2000(27).

同被引文献50

  • 1王士雯.老年多器官功能不全综合征的肺启动机制[J].中华老年多器官疾病杂志,2002,1(1):4-6. 被引量：112
  • 2李崇辉,刘巨超,张爱群,陈明易,臧传波,徐迎新,黄志强.内毒素活化和耐受的巨噬细胞差异表达基因分析[J].中华实验外科杂志,2004,21(11):1362-1365. 被引量：6
  • 3刘鸿翔,刘虹,龚建平.内毒素耐受发生机制的研究进展[J].重庆医学,2006,35(9):850-852. 被引量：4
  • 4MEDVEDEV A E,HENNEKE P,SCHROMM A,et al.Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or4[J].J Immunol,2001,167(4):2257 -2267.
  • 5WANG M J,JENG K C,SHIH P C,et al.Differential expression and regulation of macrophage inflammatory protein (MP)-1 alpha and MIP-2 genes by alveolar and peritoneal macrophages in LPS-hyporesponsive C3H/HeJ mice[J].Cell Immunol,2000,204(2):88 -95.
  • 6LI L,COUSART S,HU J,et al.Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells[J].J Bio Chem,2000,275(30):23340-23345.
  • 7LEHNER M D,MORATH S,MICHELSEN K S,et al.Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators[J].JImmunol,2001,166(8):5161 -5167.
  • 8NOMURA F,AKASHI S,SAKAO Y,et al.Cutting edge:endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression[J].J Immunol,2000,164(7):3476 -3479.
  • 9REDDY R C,CHEN G H,NEWSTEAD M W,et al.Alveolar macrophage deactivation in murine septic peritonitis:role of interleukin 10[J].Infect Immun,2001,69(3):1394-1401.
  • 10QURESHI S T,LARIVIERE L,LEVEQUE G,et al.Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (TLR4)[J].J Exp Med,1999,189(4):625 -625.

引证文献5

二级引证文献17

第三军医大学学报
2003年 第5期

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