摘要
目的 :了解曲马多作为麻醉辅助用药 ,对通气功能的影响。方法 :将30例患者随机分成曲马多组 (T组 )和哌替啶组(P组 ) ,采用曲马多2mg/kg(≤100mg/次 )及哌替啶1mg/kg(≤50mg/次 ) ,5分钟滴完后 ,观察其5、10、20、30分钟HR、SPO2、VT、VE 及动脉血气分析各项指标。结果 :P组与T组均有PaCO2 轻度上升 (P>0 05) ,P组VT、VE 及SPO2 短期下降明显并低于T组 (P<0 01) ,而T组用药前后各参数无明显变化 (P>0 05)。结论 :提示哌替啶有明显呼吸抑制作用 ,而曲马多麻醉期间辅助用药无进一步降低每分通气量之虑 ,但应注意用量及滴注速度。
Objective:To study the effects on ventilation function during anesthesia with tramadol.Methods:Thirty paˉtients were randomly divided to receive tramadol(T group)of pethidine(P group)intravenously.HR,SPO 2 ,V T ,V E and arterial blood gas parameters were determined at5,10,20,30pminutes after adminstration of tramadol(2mg.kg -1 ,≤100mg)or pethiˉdine(1mg.kg -1 ,≤50mg),respectively.Results:The PaCO 2 of both groups increased slightly(P>0.05),VT,VE and SPO 2 in P group decresed significantly,Which were significantly Lower than that in T group(P<0.01),however,the changes in above parameters were not significant before and after infusion of tramadol(P>0.05).Conclusion:It is suggested that pethidine has significant inhibition effects on ventilatory function,but tramadol has no further reduction V E during anesthesia,its dosage and drip velocity must be paid attention.
出处
《现代医药卫生》
2003年第3期266-266,共1页
Journal of Modern Medicine & Health
