摘要
目的 为取得小儿肺炎病原菌流行情况和敏感抗生素的经验。方法 对 13 2例肺炎的住院患儿的痰细菌培养及药物敏感试验结果进行统计分析。结果 该组患者共培养出致病菌 13种 ,菌株 141株 ,其中革兰阳性菌(G+菌 )占 12 .0 6% ,革兰阴性菌 (G- 菌 )占 83 .68% ,白色念珠菌占 4.2 6% ;药物敏感试验显示 ,致病菌对亚胺培南、美罗培南 (美能 )、第三代头孢菌素、喹喏酮类显示出较好的敏感率 ,G+菌并对氨苄西林 ,第一及第二代头孢菌素大多敏感 ,G- 菌并对氨基糖苷类多敏感。结论 本组结果显示小儿肺炎 G- 菌感染发生率较高 ,这与区域、病情较重有关 ,抗生素治疗应依据细菌学指导选择敏感抗生素 ,在未获明确病原菌之前 ,应根据感染的流行趋势 。
OBJECTIVE For pneumonia in children there are a variety of predominant pathogenic bacterial and antimicrobial sensitive patterns in different regions and different periods. The aim of the present study is to investigate the epidemiological characteristic of bacterial agents and their in vitro antimicrobial susceptibility in our hospital,in order to treat pneumonia in children. METHODS Identifications of bacteria were performed by using the method in ' Manual of Clinical Microbiology'. Tests were done for antimicrobial susceptibility. RESULTS From January 1997 to December 2001, 141 bacterial strains were isolated from 132 children with pneumonia. From them Gram positve bacteria, Gram negative bacteria, and Candida albicans were accounted for 12.06%, 83.68%, 4.26%, respectively.The imipenem,meropenem, the third generation cephalosporins, cyprofloxacin, norfloxacin were revealed with higher sensitivity rates to pathogenic bacteria in children with pneumonia. Gram positive bacteria also were with higher sensitivity rates to ampicillin, the first and second generations cephalosporins. Gram negative bacteria were with higher sensitivity rates to amikacin, gentamicin, tobramycin. CONCLUSIONS There were more infected rates in the children with pneumonia suffered from Gram negative bacteria than Gram positive ones. It associated with different regions and different periods. Antimicrobial treatment should be used with consideration of types of pathogenic bactreia and antimicrobial sensitive patterns. It should choice proper drugs experiencely before antimicrobial sensitive pattern was known.
出处
《中华医院感染学杂志》
CAS
CSCD
2003年第1期81-83,共3页
Chinese Journal of Nosocomiology
