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细菌性阴道病和HIV的关系研究 被引量:12

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摘要 细菌性阴道病(BV)是阴道菌群失调所致。BV增加人类免疫缺陷病毒(HIV)易感性,是促进HIV性传播的高危因素之一。阴道乳酸杆菌缺乏及菌群紊乱产生的蛋白酶破坏了生殖道黏膜免疫屏障;阴道致病微生物群刺激单核细胞和T淋巴细胞表达HIV,激活病毒转录子,增加病毒的复制。HIV增加阴道菌群的紊乱,加速HIV的传播。因此,治疗BV和克隆乳酸杆菌是防止HIV传播的新手段。
作者 王远菊
出处 《国外医学(妇产科学分册)》 2003年第1期35-38,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
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