摘要
目的总结分析平阳霉素(PYM)、地塞米松(DXM)和鱼肝油酸钠(SM)联合瘤内注射治疗口腔颌面部海绵状血管瘤(静脉畸形)的临床疗效。方法选取口腔颌面部静脉畸形350例,采用PYM、DXM、SM三药联合注射治疗。用DXM5mg/1ml,配PYM8mg,加1%普鲁卡因注射液4ml,按体表瘤体面积每1cm×1cm注射1ml混合液计算剂量,进行瘤体内注射,再按相对大剂量鱼肝油酸钠注射方法继续注射鱼肝油酸钠。每隔5～7d注射1次,3～5次为1个疗程。未愈者可重复联合治疗。结果治疗后经6～48个月随访,治愈246例(70.29%),基本治愈88例(25.14%),好转16例(4.57%),有效率为100%。结论PYM、DXM、SM联合注射治疗口腔颌面部静脉畸形,具有疗程短、不良反应小等优点,是一种安全、可靠、简便的治疗方法。
Objective:The effect of Pinyangmycin,Dexamethasonum and Sodium Morrhuate injected concomitantly to treat cavernous hemangioma in oral and maxillofacial regions was evaluated.Methods:The medical records of 350 patients with cavernous hemangioma in oral and maxillofacial regions between January1998and January2002were reviewed.One hundred and sixty-five of the patients were men,and185were women,the sex ratio was1:1.12.The patients'ages were between4months and55years.Two hundred and Twenty-six hemangiomas were located in the maxillofacial regions,and124located in the oral cavity.The size of the lesions varied from1cm×1cm to6cm×9cm.Pinyangmycin,Dexamethasonum and Sodium Morrhuate were injected simultanously into the lesions or in the vicinity of the cavernous hemangiomas,and the injection might be repeated every5to7days when necessary,and this process could be repeated3to5times.Results:Three hundred and fifty patients were followed up for6-48months.The cure and essentially cured rates were95.48%,the total efficiency rate was100%.Conclusion:This method was a safe,simple and effective therapy to manage cavernous hemangioma in the oral and maxillofacial regions.
出处
《上海口腔医学》
CAS
CSCD
2003年第1期9-11,共3页
Shanghai Journal of Stomatology
