摘要
目的 :探讨儿童郎罕细胞组织细胞病 (LCH)骨骼病变的影像学表现及其诊断价值。材料和方法 :回顾性分析经病理证实的儿童LCH 40例 ,均行X线平片检查 ,其中 8例CT扫描。 14例分别于 1个月～ 2年内随访。结果 :本组中颅骨破坏 32例 ,占 80 %;脊柱破坏 9例 ,占 2 2 .5 %;长骨破坏 13例 ,占 32 .5 %;扁骨及不规则骨破坏 4例 ,占 10 %。嗜酸性肉芽肿以颅骨、长骨和脊柱多发 ,其他类型以颅骨多发。结论 :LCH骨骼病变具有多发性、多样性和多变性的特点 ;X线平片是本症诊断的基本手段 ,CT对隐蔽部位病变及病变细微结构的显示优于平片。
Purpose: To review the radiologic manifestations of the skeletal lesions in children with langerhans' cell histocytosis(LCH),and to evaluate the means of examination in the diagnosis of LCH. Materials and Methods: The skeletal plain films of 40 pediatric patients with LCH,in which 8 cases undewent CT scans,were analysed retrospectively. All cases were confirmed by pathology. Fourteen of 40 patients were followed up from 1 month to 2 years. Results: The results showed that skull destruction presented in 32(80%),vertebra destruction in 9(22.5%),long tube-shaped bone destruction in 13(32.5%),flaty bone and irregular bone destruction in 4(10%). The most common sites of eosinophilic granulomas were the skull,vertebra and long tube-shaped bones,while Letterer-Siwe disease,Hand-Schuller-Christian disease and intermediary type maily involved skull bones. Conclusion: The x-ray features of the skeletal lesions of LCH are multifoci,diversity and changableness.Plain film is the main examination in the diagnosis of LCH.CT is superior to the plain film in revealing some hiding lesions or internal fine structure of the lesions.
出处
《中国医学影像学杂志》
CSCD
2003年第1期15-16,19,共3页
Chinese Journal of Medical Imaging
