摘要
目的 观察和比较食管鳞癌和肺鳞癌组织中人乳头瘤病毒 (HPV)感染的特点。方法 用 PCR法和原位杂交法检测 1 0 0例食管鳞癌和 49例肺鳞癌组织中的 HPV DNA并结合病理组织学研究。结果 食管鳞癌中共检出 HPV阳性 2 6例 (2 6% ) ,以 HPV1 6型为主 (1 6/2 6,61 % )。肺鳞癌中 HPV阳性 7例 (1 4 .2 % ) ,以 HPV6/1 1型为主 (6/7,86% )。结论 食管鳞癌和肺鳞癌中的 HPV感染状况有相同和不同之处 ,HPV感染的途径可能有所不同。存在
Objcetive To observe and compare HPV infection in esophageal carcinomas and lung cancers and to study the relationships between them.Methods The multiple PCR and in situ hybridization combined with the pathohistological study were used for the detection of HPV DNA in 100 cases of esophageal carcinomas and 49 cases lung cancers.Results 26 specimens were positive to HPV in esophageal carcinomas(26%),mainly HPV 16 type (16/26;61%);7 cases were positive to HPV in lung cancers (14.2%) and mostly HPV 6/11 type(6/7;86%).Conclusion There existed some identity and difference as for the HPV infectious status in esophageal carcinomas and in lung cancers.The exophytic growth were not principal growth mode in both HPV infected esophageal carcinomas and HPV infected lung cancers.
出处
《中国误诊学杂志》
CAS
2003年第2期178-180,共3页
Chinese Journal of Misdiagnostics
基金
河南省教委自然科学基础研究项目基金资助 ( 954 74 0 0 5)。
关键词
食管鳞癌
肺鳞癌
HPV感染
特点
观察
Esophageal neoplasms/Pathology
Lung neoplasms/Pathology
Papillomavirus,human
Carcinoma,squamous cell/microbiology
Papillomavirus infections
