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Relationship between hypothermia and heart rate yarialion in severe brain injury 被引量:1

Relationship between hypothermia and heart rate yarialion in severe brain injury
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摘要 AIM:To investigate effects of heart automatic nerve variations and hypothermia(HT) therapy on heart rate variation(HRV).METHODS:We studied the dynamic electrocardiagraph(ECG) of 41 cases of severe brain injury.The patients were devided into HT therapy group(n=21,body temprature 32-33℃),non-HT therapy group(n=20) and normal control(n=20).RESULTS:In group 1,the reduction of time domain indexes and frequency domain indexes were 3-6 folds and 30-50folds respectively compared with those of the control group,while the corresponding indexes reduction were 2-3 folds and 4-5folds in the group 2(P<0.05,P<0.01,respectively).The difference between groups were significant(P<0.05-0.01);the HRV reduction was more significant in the cerebrovascular accident patients than that of brain injured(P<0.05-0.01);the HRV indexes increased significantly in resuscitated patients than those in coma(P<0.01);the HRV in dead was much lower than that in survival(P=0.01).CONCLUSION:Injury of central nervous system can induce abnormal function of automatic nerve of heart and reduction of HRV.HT therapy can reduce HRV on a higher level;HRV examination can be applied into the prediction of prognosis of the brain injured. AIM: To investigate effects of heart automatic nerve variations and hypother-mia(HT) therapy on heart rate variation(HRV). METHODS: We studied the dynamic electrocardiograph (EGG) of 41 cases of seven brain injury. The patients were derided into HT therapy group( n = 21, body temprature 32 - 33℃), non-HT therapy group(n = 20) and normal control (n=20). RESULTS: In group 1, the reduction of time domain indexes and frequency domain indexes were 3-6 folds and 30-50 folds respectively compared with those of the control group, while the corresponding indexes reduction were 2-3 folds and 4-5 folds in the group 2( P < 0.05, P < 0.01, respectively). The difference between groups were significant(P < 0.05 -0.01); the HRV reduction was more significant in the cerebrovascular accident patients than that of brain in-jured(P < 0.05 - 0.01); the HRV indexes increased significantly in resuscitated patients than those in coma(P < 0. 01); the HRV in dead was much lower than that in survival(P = 0. 01). CONCLUSION: Injury of central nervous system can induce abnormal function of automatic nerve of heart and reduction of HRV. HT therapy can reduce HRV on a higher level; HRV examination can be applied into the prediction of prognosis of the brain injured.
出处 《中国临床康复》 CSCD 2003年第2期346-346,共1页 Chinese Journal of Clinical Rehabilitation
关键词 颅脑损伤 低体温 心率变异 关系 heart rate variation cardiovascular accident brain injury hypothermia therapy
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