摘要
目的 :了解张家口地区精神分裂症患者弓形虫感染状况 ,探讨弓形虫感染与精神分裂症之间的关系。方法 :采用间接红细胞凝集试验对 2 2 2例住院精神分裂症患者及 78例健康体检者进行弓形虫抗体检测。结果 :张家口地区精神分裂症患者弓形虫抗体阳性率为 7.6 6 % ,健康体检者为 1.2 8% ,两者之间差异显著 (P <0 .0 5 )。结论 :本地区精神分裂症患者弓形虫抗体阳性率高于健康人群。提示临床医务工作者应加强对弓形虫病的认识 ,重视精神病患者的弓形虫感染情况 ,对门诊和住院病人进行常规弓形虫检测。
Objective: To study the relationship between toxoplasma gondii infection and schizophrenia by investigating its infection to the patients with schizophrenia in the region of Zhangjiakou.Methods:222 in-patients with schizophrenia and 78 healthy volunteers were enrolled in this study, anti-toxoplasma gondii antibodies were detected with the IHA in all those subjects. Results:The positive rate of toxoplasma gondii antibody were 7.66% and 1.28% for the in-patients with schizophrenia and the healthy volunteers,respectively;and there was significant difference between the two groups(P<0.05). Conclusion:It was concluded that the positive rate of toxoplasma gondii antibody in the in-patients with schizophrenia in this region was higher than that in the healthy population .It is suggested that clinical medical staff should enhance the understanding of the toxoplasmosis,pay much attention to its infection to the patients with the mental disease and routine test of anti-toxoplasma gondii antibodies in the in-patients and out-patients with the mental disease.
基金
张家口市科委课题
