摘要
目的:通过观察慢性鼻窦炎(CS)不同分型粘膜炎症细胞的浸润情况,从炎症角度来探讨分析慢性鼻窦炎不同类型的变化特点、病变规律。方法:①采用HE、免疫组化、甲苯胺蓝法对粘膜组织常见炎症细胞进行染色,观察浸润情况。②采用VG染色法观察基底膜的厚度,初步分析炎症细胞浸润及其关系。结果:慢性鼻窦炎各组中炎症细胞浸润的数量明显增多,以Ⅱ型为最多,基底膜厚度与肥大细胞、CD3+淋巴细胞及嗜酸性粒细胞的数量有显著相关性。结论:不同CS分型有不同的炎症浸润特点,与临床分型所反映的病变分期趋于一致。炎症细胞在基底膜增厚中起重要的作用。
Objective: To investigate the characteristics and regularities of the different inflammatory cellulars in series clinical types of chronic sinusitis. Methods: The HE staining, immunohis-tochemical technique and toluidine blue staining were used to investigate the distribution and numbers of inflammatory cells. The Van Gieson's staining was used to observe the thickness of the basement membrances. The relationship between the quantity and the thickness of basement membrances was analyzed. The specimens of ethmord sinus mucosa membrane were obtained from 60 patients with chronic sinusitis, which were type I in 20, Type Ⅱ in 20 and type Ⅲ in 20. Results:The numbers of the inflammation cells in the lamina propria and epithelium were obviously increasing. There was more inflammation cells in type Ⅱ than that in type I and type Ⅲ . The quantity of mast cells,CD3+ cells, CD8+ cells and eosinophils were significantly associated with thickness of basement membrances. Conclusion:The characteristics of inflammatory cellulars show difference in series clinical types of chronic sinusitis, which could be associate with the pathological changes. The inflammatory cellulars may play an important role in thickness of basement membrances.
出处
《耳鼻咽喉（头颈外科）》
2003年第1期49-52,W001,共5页
Chinese Arch Otolaryngology-Head Neck Surg
关键词
鼻窦炎
T-淋巴细胞
基底膜
(Sinusitis) (T-Lymphocytes) (Basilar membrane)
