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高分辨率电喷雾飞行时间质谱测定丹参脂溶性组分 被引量:11

Determination of Fat soluble Components in Danshen by High-ResolutionElectrospray Ionization Time-of-flight Mass Spectrometry
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摘要 An excellent analytical tool for the separation and analysis of TCM(Traditional Chinese Medicine) by using HR ESI TOF MS(High Resolution Electrospray Ionization Time of flight Mass Spectrometry) was developed. A home built HR ESI TOF MS was applied to detect fat soluble components in Danshen( Salvia miltiorrhiza Bage ) directly. Compared with the method of HPLC ESI MS(High Performance Liquid Chromatograph Electrospray ionization Mass Spectrometry) method, HR ESI TOF MS method is more accurate, quick, simple and reliable, so the method can become an effective tool for the quality control of TCM. An excellent analytical tool for the separation and analysis of TCM(Traditional Chinese Medicine) by using HR ESI TOF MS(High Resolution Electrospray Ionization Time of flight Mass Spectrometry) was developed. A home built HR ESI TOF MS was applied to detect fat soluble components in Danshen( Salvia miltiorrhiza Bage ) directly. Compared with the method of HPLC ESI MS(High Performance Liquid Chromatograph Electrospray ionization Mass Spectrometry) method, HR ESI TOF MS method is more accurate, quick, simple and reliable, so the method can become an effective tool for the quality control of TCM.
出处 《高等学校化学学报》 SCIE EI CAS CSCD 北大核心 2003年第4期621-623,共3页 Chemical Journal of Chinese Universities
基金 国家自然科学专项基金 (批准号 :H -2 992 70 0 2 ) 国家自然科学重点基金 (批准号 :2 92 45 110 ) 香港特区政府创新科技署 科技部中药现代化重中之重"九五"项目资助
关键词 测定 脂溶性组分 高分辨率电喷雾飞行时间质谱 丹参 HPLC-ESI-MS 中药指纹图谱 中药分析 High resolution electrospray ionization time of flight mass spectrometry Danshen HPLC ESI MS TCM(Traditional Chinese Medicine) fingerprint
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