摘要
采用单克隆抗体免疫技术,检测了41例次某些恶性肿瘤(原发性肺癌、原发性肝癌)患者外周血T淋巴细胞(下简称T细胞)及其亚群的变化。结果表明:恶性肿瘤患者的细胞免疫功能显著低于健康成人,T细胞亚群出现明显的失衡现象。同一种恶性肿瘤而不同中医证型患者之T细胞下降水平及其亚群失衡程度不同,而属于以某一中医证型为主的不同种类恶性肿瘤患者的T细胞下降水平及其亚群失衡程度相近。从而为中医证型本质研究和中医药治疗肿瘤的机理探讨提供了科学资料。
Distribution of T lymphocyte and its subpopulation were measured in 41 cases of malignant tumour by the method of monocolonal antibodies. The results showed that (1) cellular immune function of patients with malignant tumout was lower than that of normal adults, and their T lymphocyte subpopulation appeared in imbalance; (2) The lowered level of cellular immune function and imbalance of T lymphocyte subpopulation were different in patients with the same malignant tumout but of different type on TCM Zheng-diffrentiation, yet quite similar in patients with different malignant tumours but of similar type on TCM Zheng-differentiation. These results provides scientific data for studying the characters of TCM Zheng and the mechanism of treatment of tumour with TCM.
关键词
肺肿瘤
免疫学
肝肿瘤
病机
T细胞
LUNG NEOPLASMS/pathog(TCM)
LIVER NEOPLASMS/pathog(TCM)
LIVER NEOPLASMS/immumol
TLYMPHOCYTES/immumol
