摘要
目的 探讨连续硬脊膜外腔吗啡镇痛 (CIEA)对前列腺切除术后镇痛效果和安全性。方法 选择 40例前列腺切除术后患者 ,随机分成两组 ,实验组 (CIEA) :术后 48h持续性经硬脊膜外腔导管注入吗啡 ( 0 2mg/h) ;对照组 (MI) :患者疼痛时肌肉注射哌替啶 5 0mg或其它解痉镇痛药。观察两组VAS测痛评分 ,膀胱痉挛次数、持续时间、停止冲洗时间 ,及心率、血压和呼吸频率等。结果 实验组较对照组具有镇痛效果显著 (P <0 0 1) ,膀胱痉挛次数少 ,持续时间短 ,发生率低 (P <0 0 1)等优点 ,实验组呼吸频率术后与术前无明显差异 ( P >0 0 5 ) ,恶心、呕吐、瘙痒等不良反应发生率低。结论 连续硬脊膜外腔小剂量吗啡镇痛对前列腺切除术后患者的镇痛效果良好、安全。
Objective To evaluate the analgesic effects of continuous infusion of morphine into epidural space(CIEA) on postoperative pain relief after prostatectomy. Methods 40 cases of benign prostate hypertrophy were selected and randomly divided into two groups,experimental group(CIEA),0 2mg/h of morphin was injected into epidural space,control group(MI),50mg of pethidine was injected whenever patient feel pain.VAS(Vision simulate score),frequency and duration of bladder spasm,discontinuance time of bladder irrigation,HR BP and RR,were observed. Results The experimental group was superior to the control group with characteristics of stable analgesic effect,short duration and low frequency of bladder spasm(P<0 01),the evidence of respiratory depression was not seen in any patients,there was no remarkable difference between two groups in the incidence of adverse effects such as nausea,vomiting,pruritus etc.Conclusion The analgesia effect of low dosage morphine(0 2mg/h) CIEA is well and safety for patients of postprostatectomy.
出处
《中国医师杂志》
CAS
2003年第2期171-172,共2页
Journal of Chinese Physician
