摘要
目的 :研究含丹参和葡萄糖的注射液中 5 羟甲基糠醛的检查方法。方法 :采用高效液相色谱法。结果 :选用色谱柱 :HypersilODS(4.6mm(i.d)× 2 50mm ,5 Micro) ;流动相 :甲醇 0 .5 %冰乙酸 (1 5∶85) ;检测波长 :2 84nm ;柱温 :30 °C ;可分离 5 羟甲基糠醛峰与丹参素峰 ,分离度为 :1 .8。结论 :本法简便、灵敏、准确 ,排除了丹参成分的干扰 ,可用于含丹参的葡萄糖注射液中 5
Objective: To establish the determination for 5 HMF in Glucose Injection containing the extract of Radix Salviae Miltiorrhizae. Methods: Using HPLC with Hypersil ODS [4.6mm(i.d)×250mm] column, methanol 0.5% acetic acid as a mobile phase and detection wavelength at 284nm. Results: The peak of 5 hydroxymethylfurfural was separated from the peak of Danshensu. Conclusion: The method is simple, sensitive and accurate with a good reproducibility and can be used as the quality control for Glucose Injection containing the extract of Radix Salviae Miltiorrhizae.
出处
《中成药》
CAS
CSCD
北大核心
2003年第3期191-192,共2页
Chinese Traditional Patent Medicine
