摘要
目的 :比较单双侧无抽搐电休克治疗精神分裂症患者时在抽搐时间和抽搐后能量指数及血清肌酸磷酸激酶 (CPK)方面的差异。方法 :入组患者 6 0例 ,每例做 8次无抽搐电休克治疗 ,30例前 4次作双侧 ,后 4次做单侧治疗 ,另 30例行相反程序 ,治疗指标由电休克机自动测定 ;治疗前和治疗后分别测血清CPK一次。结果 :双侧组患者在抽搐时间上明显长于单侧组 (t=17 17,P <0 0 0 1)在抽搐后能量指数上亦明显高于单侧组 (t=11 5 3,P <0 0 0 1) ;治疗前后单双侧组比较血清CPK无显著性差异。结论 :表明双侧无抽搐电休克比单侧有更明显的神经生理影响 ,即双侧比单侧有更强烈、更广泛的脑内异常放电 ;但单双侧无抽搐电休克对血清CPK的影响并无显著性差异。
Objective:The paper was to compare the differences of the seizure duration?seizure energy index and the CPK of the unilateral and bilateral ECT in schizophrenia. Methods: A comparative study was conducted 60 cases, every case was recevied 8 times therapy and all cases who received both unilateral and bilateral ECT during a single course of treatment. There were seizure duration?seizure energy index and CPK to be assessed. Results: The bilateral ECT on seizure duration is longer than the unilateral ECT (t=17.17, P<0.001); The bilateral ECT on seizure energy index is higher than the unilateral ECT(t=11.53, P<0.001); The difference of the bilateral and unilateral ECT on CPK is not significant. Conclusions:The results indicate that the bilateral ECT has more significant nerve-physiological impact than the unilateral ECT; But on CPK, the difference is not significant.
出处
《中国民康医学》
2003年第3期129-130,共2页
Medical Journal of Chinese People’s Health
