摘要
研究了杯[6]芳烃-双锰卟啉仿P450酶模型化合物对苯乙烯环氧化反应的催化性能,考察了催化剂浓度、底物浓度、氧源浓度及加入方式等对催化反应的影响.结果表明,由于具有较大疏水孔穴的杯[6]芳烃的引入,使金属卟啉的催化性能得以较大的提高,且反应遵从Michaetis-menten规律.在实验基础上,本文提出了一种可能的反应机理.
Catalytic performance of P450 enzymatic model compound with calixarene\|bismetalloporphyrins was studied and the effects of temperature, catalyst concentration, substrate concentration, NaClO concentration and the mode of adding NaClO, etc, on the reaction of styrene epoxidation were investigated. The results show that calixarene\|bismetalloporphyrin has a much higher catalytic activity than the corresponding monometalloporphyrin. This is probably due to the intaking of calixarene which has a macrocyclic ring as the hydrophobic binding site. The kinetic study indicated that the reaction obeys the Michaclius\|Menten kinetic law. On the basis of all the experimental results, a reaction mechanism was proposed.
出处
《分子催化》
EI
CAS
CSCD
北大核心
2003年第1期10-13,共4页
Journal of Molecular Catalysis(China)
基金
国家自然科学基金(N0:29572060
20272038)资助课题.
