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组织型纤溶酶原激活物及其抑制物-1与血管成形术后再狭窄 被引量:1

Effects of t-PA and PAI-1 on postangioplastic restenosis
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摘要 组织型纤溶酶原激活物 (t- PA)和纤溶酶原激活物抑制剂 - 1(PAI- 1)参与附壁血栓形成、细胞外基质 (ECM)清除和血管平滑肌细胞 (VSMC)迁移和增殖的调节 ,与血管成形术后再狭窄 (RS)的关系密切。 It is widely believed that the development of postangioplastic restenosis(RS) is related to submural thrombosis,migration and proliferation of vascular smooth muscle cells (VSMC) and extra deposition of extracellular matrix(ECM). Tissue type plasminogen activator and plasminogen activator inhibitor 1,through playing significant modulating roles in submural thrombural thrombosis deposition of ECM and migrating and proliferating of VSMC,are closely related with RS.
出处 《心脏杂志》 CAS 2003年第1期70-72,共3页 Chinese Heart Journal
关键词 组织型纤溶酶原激活物 抑制物-1 血管成形术 再狭窄 冠心病 fibrinolysis activities angioplasty,transluminal,percutaneous coronary artery restenosis
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