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朊病毒与血液制品安全性 被引量:2

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摘要 疯牛病是对牛海绵伏脑病 (BovineSpongiformEncephalopathyBSE)的简称 ,是一种慢性、具有传染性的致死性中枢神经系统疾病 ,英国于 1985年 4月首先发现该病 ,并于 1986年 11月定名为BSE ,此病的组织病理学变化和临床症状与人的库鲁病 (Kuru)、克雅氏病 (Creutzfeld Jakob ,DiseaseCJD)和羊痒病 (Scrapie)相似 ,因此 ,被认为与朊病毒 (Prion)有关 ,亦称为朊病毒病 ,其传播途径与潜伏CJD的献血者的血液和血浆是否关联 ,是人们极为关注的问题 ,本文就朊病毒的理化特性与生物学特性、传播方式。
作者 周海云
出处 《微生物学免疫学进展》 2003年第1期84-88,共5页 Progress In Microbiology and Immunology
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参考文献14

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同被引文献74

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  • 2葛秀清.输血传播变异型克雅病的风险和防范[J].中国输血杂志,2005,18(6):515-517. 被引量:1
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