摘要
目的研究肝硬变门静脉高压症患者血中血管活性肠肽水平的变化。方法以放射免疫分析法测定32例肝硬变门静脉高压症患者和对照组30例无肝脏和胰腺疾病的胆结石患者的门静脉、外周静脉和动脉血中的血管活性肠肽水平。结果肝硬变组与对照组血管活性肠肽水平的比较结果为:门静脉:104±41/71±19(P<0.01);外周静脉:89±24/50±18(P<0.01);动脉:86±21/46±15(P<0.01)。结论肝硬变门静脉高压症患者门静脉、外周静脉和动脉血中血管活性肠肽水平明显高于对照组。
Objective To investigate the changes of blood vasoactive intestinal peptide(VIP)concentrations in cir- rhotic patients with portal hypertension.Methods Radioimmunoassay was used.Results The levels of VIP were measured in the blood of 32 cirrhotic patients with portal hypertension and 30 gallstone control patients which were proved clinically and pathologically to have no hepatic and no pacreatic diseases.The VIP ratio(ng/ ml)of the cirrhosis group over the control group was:in the blood of portal veins 104±41/71±19(P<0.01); in the blood of peripheral veins 89±24/50±18(P<0.01)and in the blood of arteries 86±21/46±15(P< 0.01),Conclusion The levels of VIP in the blood of portal veins,arteries and peripheral veinous were signif- icantly higher in the cirrhotic group than in the control group.
出处
《中华普通外科杂志》
CSCD
1998年第2期91-92,共2页
Chinese Journal of General Surgery
关键词
肝硬变
门静脉高血压
血管活性肠肽
放射免疫测定
Cirrhosis
Hypertension,portal
Vasoactive intestinal peptide
Radioimmunoassay
