摘要
目的 :探讨腮腺多形性腺瘤复发、恶变的原因及临床治疗方法。方法 :对 2 2例腮腺多形性腺瘤复发患者进行回顾性分析和追踪调查。结果 :多数腮腺多形性腺瘤复发病例肿块呈多灶性 (18/ 2 2 ) ,手术越简单其复发率越高 ,复发间期越短 (P <0 .0 5 )。 2 2人中有 7例发生恶变 ,占 31.8% ,恶变与初发年龄较大有关 (P <0 .0 5 ) ,与手术次数关系不大。末次手术分别采用浅叶切除术、腮腺全切术、扩大切除术 ,对 7例有恶变者于术后辅以放射治疗。术后平均追踪 5 4月 ,除 1例多形性腺瘤恶变者于术后 30月时肿瘤复发外 ,其余均未见复发。结论
Objective:To assess the clinical presentation and treatment results of recurrent pleomorphic adenoma of the parotid gland.Methods:The clinical references of 22 patients with recurrent pleomorphic adenoma of the parotid gland were analysed retrospectively.Results:Most cases of recurrent pleomorphic adenoma of the parotid gland presented multiple nodules.A limited initial excision was more likely to result in another recurrence and a shorter disease-free interval than a more aggressive surgical procedure.Malignance was occurred in 7 of 22 patients(31.8%).A comparison between the patients who underwent malignancy and those who didn't undergo malignancy showed that primary age of the disease was significantly older in the former( P <0.05).The eventual surgery was superficial parotidectomy in 3 patients,total parotidectomy in 11 patients and radical parotidectomy in 8 patients.Seven malignant patients received adjuvant postoperative irradiation.One malignant patient reoccurred in 30 months postoperatively.The others had no recurrence in a 54-month median follow-up period.Conclusions:Inadequate surgical excision of tumor was the main cause of the recurrence of the pleomorphic adenoma of the parotid gland.
出处
《口腔医学研究》
CAS
CSCD
2003年第1期68-70,共3页
Journal of Oral Science Research
关键词
涎腺肿瘤
多形性腺瘤
复发
治疗
Salivary gland neoplasms Pleomorphic adenoma Recurrence Therapy
