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长骨骨转移癌外科治疗的随访分析 被引量:16

Surgical management of metastatic disease of long bone
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摘要 目的 为有效地提高长骨骨转移癌患者的生存质量 ,探讨外科治疗的意义及手术方案的选择。 方法 对 1990年 10月~ 1999年 10月 5 2例长骨骨转移癌患者的临床外科治疗资料回顾分析。患者男 2 7例 ,女 2 5例 ;年龄 3 3~ 74岁 ,平均 5 6 8岁 ,60岁以上的患者 3 0例 ;16例有多发转移灶 ,行外科手术 5 5个部位。采用病灶切刮骨水泥填充 3例 ;病灶切刮骨水泥填充髓内针内固定 2 9例 ;瘤骨截除人工关节置换 18例 ;瘤骨截除临时假体植入 1例 ;截肢 4例。 结果 全部患者均有随访 ,术后存活时间 2~ 12 2个月 ,平均 2 8 2个月 ,存活 6个月以上的患者 3 6例 (69 0 % ) ,存活 1年以上的患者 3 0例 (5 7 6% )。术后疼痛缓解率为 75 % ;下肢 3 6个手术部位 ,术后完全负重或扶单拐负重率为 69% ;术后复发 11例 ,复发时间为 2~ 69个月 ,平均 17 2个月 ;术后病理证实为转移癌 ,未知原发肿瘤 15例。 结论  (1)长骨骨转移癌的病理骨折内固定或预防病理骨折内固定 ,有效缓解患者的局部疼痛 ,恢复肢体负重功能或连续性 ,为术后放、化疗提供便利 ;有利于晚期骨转移癌患者的护理 ,从而提高骨转移癌患者的生存质量。 (2 )随着原发肿瘤治愈率的提高 ,单发骨转移癌病灶应行边缘性或广泛性切除 ,重建肢体功能 ,降低复发率 , Objective To improve the life quality of cancer patients with metastasis to long bone and to select suitable surgical treatment. Methods Fifty two patients with metastasis 27 men and 25 women, were treated from 1990 to 1999. Their average age was 56 8 years (33-74). In 16 patients with multiple lesions, underwent surgery at bone shaft (29 patients) and bone epiphysis (26). Thirty patients were treated for pathologic fracture and the rest for impending fracture. Operations included limb salvage (51 patients) and amputation (4) Limb salvage consisted of intralesional curettage (3 patients), intramedullary nailing reconstruction (29), endoprosthesis (18), and temporary spacer (1). 21 patients accepted postoperative chemotherapy or radiotherapy. Results Follow up of 52 patients for a mean of 28 2 months (2-122 months) showed pain relief (41 patients), (75%) and full or part weight bearing stability (36) 69%. Local tumor recurrence occurred in 11 patients. Conclusions Surgical treatment can effectively improve the life quality of patients with metastasis to long bone. The metastatic lesions should be resected with wide or radical margin for the patients with kidney, breast, prostate and thyroid cancer.
出处 《中华外科杂志》 CAS CSCD 北大核心 2003年第2期134-138,共5页 Chinese Journal of Surgery
关键词 骨肿瘤 肿瘤转移 股骨肿瘤 外科手术 治疗 Bone neoplasms Neoplasm metastasis Femoral neoplasms
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参考文献10

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同被引文献157

  • 1赵辉,廖文胜,张卫红.原发性骶骨肿瘤动脉栓塞、切除术前后的护理[J].河南外科学杂志,2001,7(4). 被引量:1
  • 2杨荣利,徐万鹏,郭卫,李南,唐顺.61例肢体转移癌的外科治疗[J].中国骨肿瘤骨病,2004,3(6):330-334. 被引量:17
  • 3姚王君.下颌骨成釉细胞瘤切除自体骨移植的护理[J].实用临床医药杂志,2005,9(6):40-40. 被引量:2
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