摘要
目的 了解江西省输血员丙肝感染情况。 方法 对东乡县、彭泽县、金溪县、九江市输血员进行随机抽样 ,用 EL ISA方法检测血清抗 - HCV、HBs Ag、抗 - HBc。 结果 72 2名输血员抗 - HCV阳性率 2 0 .78% ,输血员献全血者、献血浆者感染率各地之间均具显著性差异 (P<0 .0 0 1) ;男性输血员 HCV感染率显著高于女性输血员感染率 (χ2 =5 .0 9,P<0 .0 5 ) ;输血员≤ 35岁 HCV感染率与 >35岁组感染率有显著性差异 (χ2 =5 .89,P<0 .0 5 ) ;HCV感染与献血类型、年限和献血点数有关 ,献全血又献血浆是感染 HCV的高危因素。献血年限越长、献血点数越多 ,HCV感染率越高 ;已淘汰献血员 HCV感染率高于正常献血员感染率 (P<0 .0 0 1) ,但两者感染 HBV情况无差别 ,感染 HCV是输血员被淘汰的主要原因 ;正常献血员中抗 - HCV阳性率仍有 16 .88% ,HBs Ag阳性率仍有 1.95 %。 结论 要加强对采供血机构和血源队伍的管理。
Objective To know the state of HCV infection of blood donors in Jiangxi Province. Methods Blood donors of Dongxiang county, Pengze county, Jinxi county and Jiujiang city were randomly sampled. All serum samples were determined with ELISA. Result The total anti-HCV positive rate of blood donors was 20.78%.The HCV infection rate of full-blood donors and plasma donors were all significantly different among those investigated sites(P<0.001). The anti-HCV positive rate of male blood donors was significantly higher than that of female blood donors (χ 2=5.09,P<0.05). The anti-HCV positive rate existed difference between donors who were older than 35 and those who were 35 or younger(χ 2=5.89,P<0.05). The incidence of HCV infection for a blood donor was related to the modes, years and sites of blood transfusion. The mixed mode was a high risk factor for HCV infection. The more years and sites a blood donor transfused blood or/ and plasma, the higher incidence of HCV infection was. The HCV incidence rate of those donors sifted out was higher obviously than that of the normal donors (P<0.001), but there was no difference for the incidence of HBV infection between the two kinds of donors. HCV infection was a main cause for a blood donor being sifted out. In normal donors, anti-HCV positive rate was 16.88% and HBsAg positive rate was 1.95%. Conclusion Administration of blood transfusion organizations and blood donors should be enhanced. Gratis blood donation should be advocated extensively.
出处
《实用预防医学》
CAS
2003年第1期28-30,共3页
Practical Preventive Medicine
