摘要
目的 探讨CAF方案化疗加健脾益气、舒肝止痛中药口服对乳腺癌肝转移的治疗作用。方法 对照组单纯给以CAF方案化疗 ,治疗组在化疗基础上给以健脾益气、舒肝止痛中药及西黄丸口服。对雌激素及孕酮受体阳性者加服三苯氧胺。结果 根据世界卫生组织P实体瘤疗效评定标准 ,分为完全缓解 (CR) ,部分缓解 (PR) ,稳定 (NC)及进展 (PD)。治疗组总有效率 (CR +PR)为 83.4 %对照组总有效率 (CR +PR)为 6 3.1% ,两组总有效率存在显著差异 (χ2 =5 .6 ,P <0 .0 5 )。结论 健脾益气、舒肝止痛中药通过扶正与祛邪结合 ,既有支持强壮作用 ,又有抗癌效果 ,对提高乳癌肝转移患者的生存质量具有明显疗效 ,对化疗的减毒也有较好的作用。
Objective To detect the effects of cyclophosphamide,adroamycin and fluorouracil (CAF) chemotherapy,combined with traditional Chinese medicines on liver metastasis of mammary cancer.Methods All the patients were divided into therapeutical group (48) and control group (46).CAF,combimed with traditional Chinese medicines that reinforce the spleen to regulate qi and soothe the liver to alleviate pain,was given to therapeurical group,and CAF alone to control group.Additionally,tamoxifen was administered to patients with positive estrogen or progestone receptors.Results The total efficiencies of therapeutical group and control one were 83.3% and 63.1% respectively.There was a significant difference between them (χ 2=5.6, P<0.05).Conclusion Traditional Chinese medicines,which reinforce the spleen to regulate qi and soothe the liver to alleviate pain,not onlt only take roles in resisting tumor and strengthening bodies,but also have good effects on liver metastasis of mammary cancer.
出处
《临床军医杂志》
CAS
2003年第1期22-24,共3页
Clinical Journal of Medical Officers
关键词
乳腺肿瘤
继发性肝肿瘤
化疗
中药
mammary carcinoma
liver metastasis
chemotherapy
traditional Chinese medicine
