摘要
目的:对静脉高效丙种球蛋白(IVIG)、α-干扰素(IFN-α)及利巴韦林治疗小儿传染性单核细胞增多症疗效进行评价。方法:对142例确诊为传染性单核细胞增多症(IM)患儿随机分为三组,分别给予IVIG、IFN-α或利巴韦林治疗,对疗效进行统计学分析。结果:IVIG组、IFN-α组有效率达97.2％、92.9％,与利巴韦林组(有效率为40.0％)有非常显著的差异(P<0.01),住院时间明显缩短。结论:静脉高效丙种球蛋白、α-干扰素治疗能明显缩短传染性单核细胞增多症的病程,改善预后。
Objective: To evaluate the clinical effect of IVIG, IFN-α and ribavirin on the children with infectious mononucleosis. Methods: One hundred and forty-two children with IM were divided into three groups treated with IVIG, IFN-α and ribavirin respectively. The time of relief of manifestation was analyzed. Results: The effectual rates of IVIG group and IFN-a(97. 2% and 92. 9% respectively) were both higher significantly than that of ribavirin group ( P < 0. 01), and the hospitalization of these two groups were shortened. Conclusions: IVIG and IFN-a are effective in to treating IM.
出处
《儿科药学杂志》
CAS
2003年第1期16-17,共2页
Journal of Pediatric Pharmacy
