摘要
目的 研究长期低剂量暴露居民血稀土负荷水平及其与健康的关系。方法 选择长期生活在江西寻乌离子型稀土矿区中心地带两行政村居民为暴露组 ,同县的非稀土矿区一行政村居民为对照组 ;用ICP -MS测血稀土负荷水平 ,同时检测反映机体健康状况的 2 5项指标 ,用SPSS进行资料分析。结果 暴露组与对照组各调查 3 2 8人和2 84人 ,平均血稀土总量分别为 4 92 9和 1 684μg/L ,暴露组血稀土总量和 15种稀土元素分量均显著高于对照组 (P=0 0 0 0 )。血稀土元素中 ,含量最高的为La ,其次为Ce、Nd ,在暴露组和对照组中 ,3种元素之和分别占总量的68 72 %和 68 62 %。暴露组与对照组相比 ,收缩压降低 ,脉搏加快 ,手提转速减慢 ,白细胞数、血红蛋白、红细胞压积、血小板、血钙、血糖等指标降低 ;其中血红蛋白、血小板、血钙、血糖低于正常值者较对照组显著增多。结论 暴露组血稀土负荷显著高于对照组 ,寻乌居民血稀土以La、Ce、Nd等轻稀土元素为主。居民的稀土暴露可能对血压、脉搏、神经反射、血细胞、血钙、血糖等有一定影响。
Objective To study rare earth level in blood and its relationship with health of residents with long-time and low-level expoure.Methods To selecte two villages' residents living in rare earth ore central area as exposed group and one village residents from the same county living in non-rare earth ore area as control group.To use ICP-MS to measure residents' blood rare earth level and at the same time examine 25 index to reflect residents' health condition.SPSS was used to analyze data.Results In exposed and control groups,328 and 284 residents were studied and their average rare earth total amount in blood were 4.929 and 1.684 μg/L respectively.Rare earth total amount in blood and 15 rare earth elements in exposed group were higher than control group significantly(P=0 000).The highest amount element of rare earth elements in blood was La and then were Ce and Nd.The total proportion of La,Ce,Nd in exposed and control groups were 68 72% and 68.62% respectively.In exposed group,systolic blood pressure was lower,pulse was more rapid,hand twist speed was slower and WBC,HGB,HCT,PLT,blood Ca,blood glucose were lower than those in control group.Residents whose HGB,PLT,blood Ca,blood glucose lower than normal value were much more in exposed group than in control group significantly.Conclusion Rare earth level in blood in exposed group was higher than in control group significantly.Rare earth in blood of residents in Xunwu was mainly La,Ce,Nd and other light rare earth elements.Residents' exposure to rare earth may influence blood pressure,blood cell,nervous reflection,blood Ca and glucose.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2003年第2期133-135,共3页
Chinese Journal of Public Health
基金
国家自然科学基金资助 (398690 0 3)
关键词
血
稀土负荷
居民
健康状况
环境流行病
rare earth
health
environmental epidemiology
prevalence survey
