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P物质与急、慢性胰腺炎的关系

Relationship of substance P and acute or chronic pancreatitis
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摘要 近 10年来的研究发现 ,胰腺炎时 ,胰腺中P物质水平及其受体NK 1R的表达均明显增加 ,与胰腺组织血浆外渗、损害程度以及慢性胰腺炎疼痛关系密切。作者就近年来一些相关文献作一综述 。 In last ten years, it has been found that both substance P and its receptor neurokinin 1 receptor (NK?1R) are increased in the pancreas during pancreatitis.Substance P and NK?1R have showed close relation with pancreatic plasma extravasation, the severity of acute pancreatitis and generation of pain in chronic pancreatitis.The present review summarized the discoveries in this field within recent years,and clarified the role of substance P and its receptor in the pathogenesis of pancreatitis.
作者 霍明东 高乃荣 石欣
机构地区 东南大学附属中大医院普外科
出处 《东南大学学报（医学版）》 CAS 2003年第1期61-63,共3页 Journal of Southeast University(Medical Science Edition)
基金 ~~
关键词 P物质 受体 神经激肽1 胰腺炎 综述 substance P receptors,neuropeptide pancreatitis review literature
分类号 R657.51 [医药卫生—外科学]
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参考文献14

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东南大学学报（医学版）
2003年 第1期

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