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出生缺陷388例临床研究 被引量:19

Clinical stuty on 388 cases of birth defect
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摘要 目的 探讨出生缺陷发生的种类、相关因素及防治措施。方法 对 2 6年间出生缺陷病例进行回顾性临床分析。结果  2 6年间出生缺陷的平均发生率为 11 5‰。 1975~ 1990年间的发生率为 14 19‰ ,1991~ 2 0 0 0年间的发生率为 6 0 3‰。两个时期比较 ,1975~ 1990年间出生缺陷的类型以神经管缺陷为主 ,1991~ 2 0 0 0年间出生缺陷的类型以软组织畸形为主。 10月份出生缺陷的发生率较高。结论 出生缺陷儿的发生与营养、季节、环境及遗传因素有关。出生缺陷的防治应以预防为主 ,并应采用B超、生化等手段早期筛查畸形儿 。 Objective To study the types,related factors,prevention and treatment of birth defect.Methods Through retrospective clinical study,all the clinical data of the perinatal fetuses with birth defect during the period of 1975 to 2000 were reviewed.Results The mean birth defect rate in this hospital was 11 5‰,while this rate was 14 19‰ during the period of 1975~1990 and 6 03‰ during the period of 1991~2000.The prevalence of NTD has decreased significantly between these two time intervals.Two very rare cases of birth defect are presented.Conclusion The occurrence of birth defect is related to nutrition,season,environment and genetic factors.Prevention should be focused on.It is advisable to screen the birth defect by means of ultrasonography and biochemical measures as early as possible and give proper treatment.
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2003年第1期35-36,共2页 Chinese Journal of Practical Gynecology and Obstetrics
关键词 出生缺陷 临床研究 围生期 影响因素 Birth defect Deformity Perinatal period
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  • 1李竹 钱宇平.出生缺陷监测 第2版[M].北京:人民卫生出版社,1993.236.

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