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维甲酸在高氧肺损伤中作用的研究新进展

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摘要 近年研究表明,长时间吸入高浓度氧(简称高氧)可抑制肺泡Ⅱ型上皮细胞生长,导致细胞外基质合成和降解失衡,进而阻碍新生儿肺发育。维甲酸是维生素A在体内的主要活性形式,可促使肺泡上皮细胞增殖,调节细胞外基质含量,促进肺发育成熟。本文就高氧对肺发育的影响及维甲酸对肺发育、高氧肺损伤的作用作一简要概述。
作者 容志惠
出处 《国外医学(儿科学分册)》 2003年第1期13-15,共3页 Foreign Medical Sciences(Section of Pediatrics)
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