摘要
目的 观察雾化吸入利多卡因在激素依赖型哮喘中的治疗作用。方法 治疗组 11例 ,采用 2 %利多卡因溶液雾化吸入 ,对照组 10例 ,给予生理盐水雾化吸入。 2周后 ,所有患者激素量减半 ,分别测两组患者激素减量前及激素减量 2周后FEV1 及症状评分。结果 治疗组激素减量前后FEV1 及症状评分无明显差异 (P >0 .0 5 )。对照组激素减量后FEV1 较减量前下降 ,症状评分较减量前升高 ,其差异有显著性 (P <0 .0 0 5 )。
Objective: To evaluate the effects of the inhalation of lidocaine on the treatment of steroid dependent asthma.Methods: eleven patients with steroid dependent asthma were inhaled 2% lidocaine solution as experimental group,and ten patients with steroid dependent asthma were inhaled 0.9% sodium chloride solution as controled group. After two weeks,a dose of corticosteroid decreased to half of the dose before in all patients.Observe their FEV 1 and symptom scope before the dose of corticosteroid decreased and two weeks after the dose of corticosteroid decreased.Results: In experimental group,before and after the dose of corticosteroid decreased the level of FEV 1 and symptom scope showed no significant difference (P>0.05).In controled group,two weeks after the dose of corticosteroid decreased,FEV 1 and symptom deterioration was significant (P<0.005).Conclusion: Lidocaine inhalation may help the asthma patient with steroid dependence reduce their dose of corticosteroid,and help control their symptom.
出处
《海南医学》
CAS
2003年第1期20-21,共2页
Hainan Medical Journal
