摘要
本文采用54例活检和5例尸检的鼻咽部组织,从不典型增生、鼻咽癌的癌旁组织、微小浸润癌及鼻咽癌颅底侵犯等不同情况,在电镜下着重观察癌细胞的侵袭方式。观察证明间变细胞和癌细胞的侵袭方式类似阿米巴的阿米巴运动,其假足穿过缺损的基底层侵入癌旁组织。
This article describes the morphological charateristies of nasopharyngeal cancer cells invasion proved by electron microscopy. The results suggested that the processes of invasion of the nasopharyngeal cancer cells can be divided into three stages, namely:a, the cytoplasmic base of anaplasia cells or cancer cells extended numerous filopodia, the latter lead tO waves or/and local loss of basement membrane, then, cancer cells by thire pseudopodia through defective basement membrane penetrated into the underlying interstitial stroma; b, because cancer cells possess capable of ac-tive locomotion, the invading cancer cells by amiboid movement actively migrate into the direction of least resis-tance, and the cancer cells will proliferate when active translatory movement cease, such migration/proliferation cy-cle is repeated, and the tissue pressure proliferating tumor lead to degradation of surrounding tissues; C, the in-vading cancer cells penetrated wall of vessels for further distant metastasis, therefore invasion is an essential part of the metastatic process.
出处
《电子显微学报》
CAS
CSCD
1992年第1期1-4,共4页
Journal of Chinese Electron Microscopy Society
关键词
鼻咽癌
细胞
侵袭
电镜
Human Nasopharyngeal Carcinoma,Invasion,Amiboid Movement,Transmission Electron Microscope
