期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

用SnaP Shot的方法对线粒体7146位点进行基因分型 被引量：1

Genotype the Locus 7146 on mtDNA by SNaP Shot Method
在线阅读 下载PDF
导出
摘要 利用SNaPShot的方法对线粒体7146位点在7300人的样品中进行基因分型,这个位点在非洲人群中存在2种等位基因,但是在非非洲人群中仅存在突变型.这个研究对利用线粒体研究人类进化,特别是对东亚人群的起源有较大的应用价值.同时还建立了一套大规模、高通量的SNP分型技术平台. Locus 7146 was genotyped by SNaP Shot method in 7 300 samples. The locus was proved to be just one allele in Asian, but two alleles were found in African. This is much useful for the human evolutionary research, especially for research about EastAsian population evolution.
作者 柯玉雄 卫灿东 金建中 金力
机构地区 复旦大学生命科学学院遗传学研究所
出处 《复旦学报（自然科学版）》 CAS CSCD 北大核心 2002年第6期618-620,共3页 Journal of Fudan University：Natural Science
关键词 SNAP Shot 线粒体 基因分型 单核苷酸多态性 现代人 起源 遗传学 single nucleotide polymorphism recurrent mutation phylogenetic tree
分类号 Q981.1 [天文地球—古生物学与地层学] Q987 [生物学—遗传学]
  • 相关文献

参考文献7

  • 1Su B, Xiao J, Underhill P, et al. Y-Chromosome evidence for a northward migration of modern humans into Eastern Asia during the last Ice Age[J]. Am J Hum Genet, 1999, 65(6): 1718-1724.
  • 2Ke Y H, Su B, Song X F, et al. African origin of mordern humans in East Asia: A total of 12 000 Y chromosomes[J]. Science, 2001, 292(5519): 1152-1154.
  • 3Torroni A ,Bandelt H J,D'Urbano L, et al. mtDNA analysis reveals a major late Paleolithic population expansion from southwestern to northeastern Europe [J]. Am J Hum Genet, 1998, 62(5): 1137-1152.
  • 4Torroni A, Huoponen K, Francalacci P, et al. Classification of European mtDNA from an analysis of three European poplations [J]. Genetics, 1996. 144(4): 1835-1850.
  • 5姚永刚,张亚平.线粒体DNA和人类进化[J].Zoological Research,2000,21(5):392-406. 被引量：18
  • 6Hecker K H, Taylor P D, Gjerde D T. Mutation detection by denaturing DNA chromatography using fluorescently labeled polymerase chain reaction products [J]. Anal Biochem, 1999, 272(2): 156-164.
  • 7Makridakis N M, Reichardt J K. Multiplex automated primer extension analysis: Simultaneous genotyping of several polymorphisms [J]. Biotechniques, 2001, 31(6): 1374-1380.

二级参考文献2

共引文献17

同被引文献17

  • 1欧雪玲,赵方,许传超,伍新尧,区敬华.应用基质辅助激光解吸电离飞行时间质谱技术检测载脂蛋白E基因多态性[J].中山大学学报（医学科学版）,2004,25(6):564-567. 被引量：4
  • 2李莉,李荣宇,李成涛,柳燕,林源,阙庭志,孙美倩,李瑶.31个SNP位点多重PCR扩增和芯片分型技术的建立及其法医学应用[J].法医学杂志,2005,21(2):90-95. 被引量：10
  • 3Harald Niederst?tter,Michael D. Coble,Petra Grubwieser,Thomas J. Parsons,Walther Parson.Characterization of mtDNA SNP typing and mixture ratio assessment with simultaneous real-time PCR quantification of both allelic states[J]. International Journal of Legal Medicine . 2006 (1)
  • 4Aydin A,Baron H,Bahring S,et al.Efficient and cost-effective Single Nucleotide Polymorphism detection with different fluorescent applications. Biotechniques . 2001
  • 5Clegg RM,,Murchie AI,Zechel A,et al.Fluorescence resonance energy transfer and nucleic acids. Methods in Enzymology . 1992
  • 6Tyagi S,Kramer F R.Molecular beacons: probes that fluoresce upon hybridization. Nature Biotechnology . 1996
  • 7Kostrikis L G,Tyagi S,Mhlanga M M,et al.Molecular beacons: spectral genotyping of human alleles. Science . 1998
  • 8Pastinen T,Raitio M,Lindroos K,et al.A system for specific, high-throughput genotyping by allele-specific primer extension on microarrays. Genome Research . 2000
  • 9Hiratsuka M,,Tsukamoto N,,Konno Y, et al.Forensic assessment of 16 single nucleotide polymorphisms analyzed by hybridization probe assay. Tohoku Journal of Experimental Medicine . 2005
  • 10Niederstatter,H,Coble,MD,Grubwieser,P,Parsons,TJ,Parson,W.Characterization of mtDNA SNP typing and mixture ratio assessment with simultaneous real-time PCR quantification of both allelic states. International Journal of Legal Medicine . 2006

引证文献1

复旦学报（自然科学版）
2002年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部