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血管紧张素转换酶基因多态性与老年人脑梗塞的相关性研究

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摘要 目的 探讨血管紧张素 - I转换酶基因多态性与老年人脑梗塞的相关性及预后分析。方法 应用一步 PCR三条引物法对 1 2 6例老年性脑梗塞 (脑梗塞组 )和 30 1例正常老年人 (对照组 )进行血管紧张素 - I转换酶基因多态性分析并进行基因型及等位基因频率计数 ,组间采用 χ2检验进行统计学分析。结果 脑梗塞组 DD型基因频率及 D等位基因频率分别为 2 0 .6%和 37.7% ,对照组分别为 9.3%和 31 .2 % (P<0 .0 5)。结论 血管紧张素 - I转换酶基因多态性与老年人脑梗塞有相关性 ,对老年人脑梗塞预后分析有一定意义。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2003年第1期20-21,共2页 Chinese Journal of Gerontology
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