摘要
目的 探讨非瓣膜病性房颤患者中发生缺血性卒中的危险因素。方法 回顾分析近年来非瓣膜病性房颤患者中合并缺血性卒中者 5 0例 ,以同期不合并卒中的 5 0例为对照组 ,分析非瓣膜病性房颤合并缺血性卒中的临床及心超危险因素 ,并用非条件logistic回归模型进行多因素分析。结果 在缺血性卒中组 ,大于 65岁者明显多于对照组 (P <0 .0 5 ) ,房颤的病程明显长于对照组 (P <0 .0 5 )。缺血性卒中组中吸烟、既往卒中或TIA发作、充血性心力衰竭、高血压病、糖尿病、左心室功能减退与左心室射血分数降低的病例明显多于对照组 (P <0 .0 5 )。多因素非条件logistic回归分析发现 ,非瓣膜病性房颤合并缺血性卒中的发生与年龄、高血压病、糖尿病、既往卒中或TIA发作史与左心室功能减退有关。结论 高龄、高血压病、糖尿病。
Purpose: To assess the risk factors for ischemic stroke in nonvalvular atrial fibrillation (NVAF). Methods: All patients with or without ischemic stroke in NVAF were retrospectively analyzed, each group was 50 cases. The risk factors of clinical condition and echocardiographic features were compared between these two groups. Unconditional logistic regression analysis was used for multivariate analysis. Results: The number of patients aged ≥65 in the ischemic stroke group was much more than that in the control group(P<0.05). The course of atrial fibrillation(AF) in the ischemic stroke group was longer than that in the control group (P<0.05). The number of patients in the ischemic stroke group, who had hypertension, history of smoking, prior stroke or transient ischemic attack (TIA), abnormal left ventricular (LV) function or LV ejection fraction, congestive heart failure and diabetes mellitus, was more than that in the control group(P<0.05). The results of multivariate logistic analysis showed that age, prior stroke or TIA, abnormal LV function, diabetes mellitus and hypertension were positively related to ischemic stroke in NVAF. Conclusions: The independent risk factors for ischemic stroke in NVAF included: age, hypertension, prior stroke or TIA, abnormal LV function and diabetes mellitus.
出处
《复旦学报（医学版）》
EI
CAS
CSCD
北大核心
2003年第1期77-79,共3页
Fudan University Journal of Medical Sciences
