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关节软骨损伤MR成像序列的实验研究 被引量:1

MR Imaging Sequences in Hyaline Cartilage Defects: An Experimental Study
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摘要 目的 评价关节软骨缺损检查的各种MRI扫描序列。材料与方法 选用猪膝关节 10只 ,制成宽度不等、深度为软骨全层的小槽状软骨缺损。MRI序列包括T1加权自旋回波序列 (SE T1)、质子和T2 加权快速自旋双回波序列 (FSE PD/T2 )、附加脂肪抑制的质子和T2 加权快速自旋双回波序列 (FS FSE PD/T2 )、附加脂肪抑制的三维快速扰相梯度回波序列 (FS 3D SPGR)、液体衰减反转恢复序列 (FLAIR)、短TI翻转回波序列 (STIR)和T1加权反转恢复序列 (IR TI 70 0 )。结果 与常规膝关节检查的FSE PD/T2 序列比较 ,FS FSE PD/T2 能够分辨软骨与软骨下骨的界限 ,可测量软骨缺损厚度和深度 ;FS 3D SPGR的软骨信噪比 (SNR)和其对软骨下骨、关节液等关节软骨周围组织的对比噪声比 (CNR)最高 ;IR TI 70 0测量的软骨缺损宽度和深度 ,与实际测量值的一致性最好 ,FLAIR和STIR不能清楚分辨软骨和软骨下骨的界限。结论 FS FSE PD/T2 应作为膝关节检查的常规序列 ;三维抑脂梯度回波序列仍为关节软骨检查的最佳扫描序列 ; Objective To evaluate different MR imaging sequences in detecting hyaline cartilage defects.Materials and Methods Cartilage defect was established in 10 pig knees, which were scanned with nine different sequences on a 1.5T MR scanner. MRI sequences included 2D sagittal T 1 weighted spin echo (SE), dual echo T 2 weighted/proton density weighted fast spin echo (FSE PD/T 2), FSE PD/T 2 with fat saturation (FS FSE PD/T 2), 3D fast spoiled gradient echo with fat saturation (FS 3D SPGR), fluid attenuation inversion recovery (FLAIR), short T1 inversion recovery (STIR) and T 1 weighted inversion recovery (IR TI700). A comparison of the image qualities between different sequences was made.Results Compared with routinely used FSE PD/T 2 for knee joint, FS FSE PD/T 2 image could more clearly distinguish the cartilage and subcartilaginous bone, and precisely measure the width and depth of cartilage defects. FS 3D SPGR showed the highest cartilage SNR and highest CNR between cartilage and adjacent tissue (such as subcartilaginous bone, articular fluid, etc.). IR TI700 sequence gave the best accuracy for the measurement of both the width and depth of cartilage defects, being in excellent agreement with the actual results. FLAIR and STIR could not well distinguish the cartilage and subcartilaginous bone.Conclusion FS FSE PD/T 2 should be routinely used for knee joint examination although 3D fat saturation gradient echo sequence is still the optimal scanning sequence for displaying articular cartilage. Inversion recovery sequence carries potential clinical value in the examination of cartilage.
出处 《临床放射学杂志》 CSCD 北大核心 2003年第1期67-72,共6页 Journal of Clinical Radiology
基金 辽宁省社会发展基金资助项目
关键词 磁共振成像 关节软骨损伤 MR成像序列 实验研究 Knee joint Articular cartilage MRI
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