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纹状体中神经元活动的多巴胺调节 被引量:4

Dopaminergic modulation of neuronal activity in the striatum
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摘要 纹状体参与机体各种不同的行为活动 ,这些活动主要依赖于完整的多巴胺能神经支配 ,最近的电生理研究表明多巴胺通过改变电压依赖性的通道传导和突触传递来调节靶细胞的活动。 The striatum is involved in diverse behaviors which depend on intact dopaminergic innervation. Recent electrophysiological studies have revealed that dopamine alters both voltage dependent conductances and synaptic transmission, resulting in state dependent modulation of target cells. This review makes clear predictions about how dopamine should alter the responsiveness of striatal neurons to extrinsic excitatory synaptic activity.
作者 刘昀 胡刚
出处 《中国药理学通报》 CAS CSCD 北大核心 2003年第1期5-8,共4页 Chinese Pharmacological Bulletin
基金 国家自然科学基金资助项目 No 39970 846
关键词 纹状体 神经元 多巴胺 striatum neuronal dopamine
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