摘要
目的 探讨新生儿惊厥的远期预后与围生期疾病及惊厥情况的关系。 方法 对5-12岁有新生儿惊厥史的儿童进行体格检查及IQ测定,部分行CT及EEG检查并回顾病史和出生情况。 结果 后遗症(脑瘫、癫(?)和智力低下)发生率为26.8%(15/56)。其中脑瘫4例、癫(?)5例(2例合并脑瘫)、智商低下12例(3例合并脑瘫,1例合并癫(?));新生儿缺血缺氧脑病、惊厥次数≥3、持续48 h以上、全身强直阵挛型和多灶性阵挛型患儿后遗症发生高。 结论 新生儿惊厥可致神经系统后遗症,预后与其病因、惊厥次数、惊厥持续时间和惊厥形式密切相关。
Objective To evaluate long-term prognosis in neonates with convulsion and its related factors. Methods Fifty-six infants with convulsion were studied. All of them received systemic physical examination and intelligence test, and some of them underwent CT and EEG examination. The relationship among prognosis, situation of perinatal , stage and convulsion was explored. Results In all infants, 15 (26.8%) had nervous system sequela. Cerebral palsy developed in four infants, and five (including two infants with cerebral palsy) suffered from epilepsy. Twelve infants had low IQ (three infants with cerebral palsy and one with epilepsy). Neonatal convulsions caused by HIE were significantly different from those caused by other factors (P<0. 05). Additionally, prognosis was highly correlated with, convulsion styles, the number of seizure times and seizure duration. Conclusion A high correlation exist between neonatal convulsions' preognosis and its etiology, convulsion styles, the number of seizure times and seizure duration.
