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壳聚糖纳米粒的研究进展 被引量:29

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摘要 壳聚糖是一类带正电的直链多糖 ,具有良好的生物相容性和生物可降解性 ,且具有多种生物活性 ,能有效增加药物通过眼部、鼻腔及胃肠道粘膜上皮的吸收 ,降低药物的吸收前代谢 ,提高药物的生物利用度 ,因此壳聚糖在缓控释给药系统中具有广阔的应用前景 ,但其溶解性能有待于进一步提高。本文就壳聚糖纳米粒的制备方法、作用特点及应用作一概述。
作者 徐连敏
出处 《国外医学(药学分册)》 2002年第6期329-332,共4页 Foreign Medical Sciences(Section of Pharmarcy)
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