摘要
心肺脑复苏 ( cardiopulmonary cerebral resuscitation) CPCR是对临床死亡及前期采取的心肺脑功能抢救措施。对象是各种原因引起的呼吸心跳骤停患儿。目前认为 CPCR抢救最关键的时机是最初 1～ 4min,肾上腺素是公认 CPCR的首选药物 ,以往认为中小剂量增加房室心肌收缩力 ,增加心率 ,是复苏的优点 ,现主张复苏时间用大剂量肾上腺素 ;碱性药物的使用原则应晚用 ,少用 ,慎用 ;CPCR间期宜用无糖液或 5 %的低糖液 ,快速大量输注葡萄糖对 CPCR是不利的 ;呼吸重建气管内插管在 CPCR中是首选方法 ,呼吸兴奋剂已不主张使用 ;静脉和气管内给药在 CPCR中首选 ,并提出骨髓内给药 ;心内注射给药虽然药效确切 ,但干扰胸外按压 ,并可导致心肌冠脉损伤 ,现已渐废弃 ;钙剂已不做为复苏的常规用药 ;脑复苏药包括纳洛酮现仍处在临床观察阶段。
CPCR is measures taken to rescue the cardiopulmonary cerebral functions during the clinical death and its pre period.All kinds of sudden cardiopulmorary deaths in children are its object.Its deemed that the most crucial opportunity of CPCR is initially 1 to 4 minutes at present.Epinephrine is considered the first choice resuscitation drug.The previous rescue advantages were increasing atrium ventricle myocardial contraction and heart rate when using middle to small dosage.The present view is to use large dosage epinephrine during resuscitation.Basiclly alkaline drugs should be used later,fewer and carefully.Non or 5% lower glucose solution should be used among CPCR.The first choice method is to re build breathing way by intratracheo intubation.Breathing excitant hasnt maintained to use.Taking medicine of viaintraventrous and via intratrocheal should be first choiced and intramarrow injection has also raised.Although introcardial injection has its definite efficacy,then owing to its interfering with heart massage and may cause coronary arteries damage,the injection has been discarded gradually.The conventional drugs of resuscitaion havent included calcium.The drugs of cerebral resuscitation such as naloxone are still at the stage of clinical observation.
出处
《延安大学学报（自然科学版）》
2002年第4期66-68,共3页
Journal of Yan'an University：Natural Science Edition
