1Folkman J. What is the evidence that tumors are angiogenesis dependent ? J Natl Cancer Inst, 1990,82: 4 ~ 6.
2Neufeld G,Cohen T,Gitay H,et al. Similarities and differences between the vascular endothelial growth factor (VEGF)splice variants. Cancer Metastasis Rev, 1996,15:153~ 158.
3Yamamoto S,Kanishi I,Mandai M ,et al. Expression of vascular ehdothelial growth factor (VEGF)in epithelial ovarian neoplasms:correlation with clinicopathology and patient survival,and analysis of serum VEGF levels. Br J Cancer, 1997,76 (9): 1221~ 1227.
4Shweiki D,Itin A,Soffer D,et al. Vasculai endothelial growth factor induced by hypoxia may mediate hypoxia-intiated angiogenesis.Nature, 1992,359.. 843~845.
5Jie MU,Yoshiko A ,Tateki T,et al. Inhibition of growth and metastasis of ovarian carcinoma by administering a drug capable of interfering with vascular endothlial growth factor activity. Jpn J Cancer Res,1996,87:963~971.
6Timothy A,Mohanraj D,Sabita R,et al. Targeting the tumor vasculature: inhibition of tumor growth by a vascular endothlial growth factor-toxin conjugate. Int J caancer,1997,73:865~870.
2TAKAHASHI Y,KITADAI Y,BUCANA CD,et al.Expression of vascular endothelial growth factor and its receptor,KDR,correlates with vascularity,metastasis and proliferatin of human colon cancer[J].Cancer Res,1995,55:3964-3968.
3HARTENBACH EM,OLSON TA,GOSWITZ J J,et al.Vascular endothelial growth factor(VEGF)expression and survival in human epithelial ovarian carcinomas[J].Cancer Lett,1997,121:169-175.
4GARZ GG,GIAVATTNI A,LUCARINI G,et al.Vascular endothelial growth factor expression as a prognostic index in serous ovarian cystoadenocarcinomas:relationship with Mib1 immunostaining[J].Gynecol Oncol,1999,73:396-401.
5Toi M, Matsunmoto T, Bando H. Vascular endothelial growth factor: its prognostic, predictive, and therapeutic implications [ J ].Lancet Oncol,2001,2 ( 11 ) :667 ~ 673.
6Brekken RA, Thorpe PE. Vascular endothelial growth factor and targeting of solid rumors[ J]. Anticancer Res, 2001,21 (6B):4221 ~ 4229.
7Holash J,Maisonpierre PC,Compton D,et al.Vessel cooption,regression,and growth in tumors mediated by angiopoietins and EGF[J].Science,1999,284(5422):1994~1998.
8Fujimoto J,SakaguchiH,AokiI,et al.Clinicanimplications of expression of vascular endothelial growthfactorinmetastaticlesions of ovarian cancers[J].Br J Cancer,2001,85(3):313~316.
9Yamamotos S, Konishi I, Mandai M, et al. Expression of Vascular endothelial growth factor (VEGF) in epithelial ovarian nepolims:Correlation with clinicopathology and patient survvivaal analysis of serum VEGF levels[J]. Br J Cancer,1997,76(9) :1221 ~ 1229.
10Duyndam MC, Hilhorst MC, Schluper HM, et al. Vascular endothelial growth factor165 overexpression stimulates in human ovarian cancer xenografts[ J]. Am J pathol,2002,160:537 ~548.