摘要
用荧光定量法测定了76例流行性出血热(EHF)患者不同病期尿中去甲基肾上腺素(NE)和肾上腺素(E)的含量。结果发现:各病期含量(μg/24h)分别为发热期91.44±88.81,低血压少尿期86.27±73.95,多尿期103.87±82.80,恢复期88.46±64.95,较对照组(38.56±10.47)明显增高,(P<0.01),提示交感肾上腺髓质在EHF发病过程中处于激发状态,治疗中应避免使用缩血管药物。
The value of uric norepinephrine (NE) and epinehrine (E) in 76 cases with epidemic hemorrhagic fever (EHF) was studied by fluorescein quantitative determination. It was found that the contents of uric NE and E of the EHF patients were much higher than those of the normal controls (P<0.01 ). The results were as follows: febrile phase 91.44±88.81 (μg/24 h), hypotensive and oliguric phase 86.27 ± 73.95, diuretic phase 103.87± 82.80, convalescent phase 88.46±64.95, control group 38.56±10.47. It suggests that NE and E may play an important role in the pathogenesis of fever, shock and renal dysfunction in EHF. The results reveal that the adrenal medulla is in excited state in the course of EHF, so the vasoconstriction should not be taken.
出处
《第四军医大学学报》
1992年第1期54-55,共2页
Journal of the Fourth Military Medical University
关键词
出血热
流行性
去甲肾上腺素
hemorrhagic fever, epidemic
norepinephrine
epinephrine
renal dysfunction
shock
