摘要
观察了13名男性青年于摸拟4000m及5000m停留72h肺血流图变化。发现紧张期指数(Q—aI)逐渐延长。主波振幅、充盈速度和主波最大上升速度逐渐下降。5 000m时Q—a/RVET从对照值0.3194±0.010增至0.406±0.016(P<0.05)。 上述结果提示,急性进入高原人体在持续缺氧刺激下可导致肺血管收缩,肺动脉压升高,继续上升至5000m时可出现心功能降低。
The effects of the alterations of high altitude(at 4 000m for 48h and then at 5 000m for 24h)on the pulmonary rheography were investigated in 13 healthy male volunteers.It was found that the tonic interval index(Q-aI)was gradually prolonged jthe amplitude,the mean rate of filling and the maximal ascending rate of the systolic wave were gradually decreased.When the volunteers were exposed to 5 000m,the Q-aI/RVET was increased from the sea-level value to 0.319?.010 to 0.400?.016(P<0.05)and the Q-aI was prolonged from 141.3±3.5 to 151.3±5.5 ms(P<0.05).The changes of amplitude,the mean rate of filling and the maximal ascending rate of the systolic wave were also more obvious than those at 4 000m(P<0.05).These findings indicate that acute hypoxia can contract the pulmonary vessels to result in pulmonary arterial hypertension and to reduce the compliancy of the pulmonary vessels.These,in turn,can further decrease the functions of the heart.
出处
《第三军医大学学报》
CAS
CSCD
北大核心
1992年第4期352-354,共3页
Journal of Third Military Medical University
关键词
高海拔
体积描记术
心脏功能试验
altitude
plethysmography
impedance
heart function tests
