摘要
目的:对比静滴哌拉西林与静滴哌拉西林加支气管肺泡灌洗(BAL)治疗下呼吸道感染的疗效、疗程。方法:进行前瞻性、随机比较。静滴哌拉西林组(A组)41例,哌拉西林4.0g+生理盐水100mL,12h静滴1次。静滴哌拉西林+BAL组(B组)35例,哌拉西林4.0g+生理盐水100mL,12h1次,入院第2d晨行BAL。两组患者的一般资料相似(P>0.05)。结果:两组临床疗效差异无显著性(P>0.05),分别为78%和83%。两组的疗程有显著性差异,A组为13d,B组为7d。结论:在治疗下呼吸道感染时,静滴哌拉西林与静滴哌拉西林+BAL治疗都是安全、有效的,但后者可以缩短疗程,且患者耐受性良好。
Objective: To compare the curative effect and the treatment course of two therapies——intravenous drip of piperacillin
and intravenous drip of piperacillin integrated with bronchoalveolar lavage (BAL) for treating lower respiratory tract infection. Metholds:Prospective and random comparative study was made in our hospital. In group A 41 patients were given piperacillin ,4 grams every 12 hs by intravernous drip. In group B (36 cases) 4g of pipercillin by intravemous drip every 12 hs was followed by BAL in second morning.The general date of these two groups were similar (P > 0.05) .Results:The curative effects of these two groups ware 78 % and 83 % , respectively. So there was no significant difference between the tow groups ( P > 0.05). But the course of treatment significantly differed in group All days, and in group B 7 days) .Conclusion: In treating lower respiratory tract infection, both the inethods of cure are safe and effective. But intraverous drip of piperacillin integrated with bronchoalveolar lavage can shorter the course of treatment and is well tolerated for the patients.
出处
《医学理论与实践》
2002年第12期1397-1398,共2页
The Journal of Medical Theory and Practice
关键词
静滴
哌拉西林
支气管肺泡灌洗
治疗
下呼吸道感染
疗效观察
Intraverous drip,Piperacillin,Bronchoalveolar lavage(BAL), Lower respirator tract infection