期刊文献+

转化生长因子-β与转基因治疗肝纤维化 被引量:2

原文传递
导出
出处 《中华消化杂志》 CAS CSCD 北大核心 2002年第10期621-623,共3页 Chinese Journal of Digestion
  • 相关文献

参考文献14

  • 1梁志清,何振平.贮脂细胞TGF-β1反义基因转移及对细胞外基质合成的抑制作用[J].中华医学杂志,1998,78(11):850-852. 被引量:13
  • 2Fujimoto J, Kaneda Y. Reversing liver cirrhosis: impact of genetherapy for liver cirrhosis. Gene Ther, 1999,6:305-306.
  • 3George J, Roulot D, Koteliansky VE, et al. In vivo inhibition ofrat stellate cell activation by soluble transforming growth factor betatype Ⅱ receptor:a potential new therapy for hepatic fibrosis. ProcNad Acad Sci USA, 1999,96:12719-12724.
  • 4George J, Wang SS, Scvcsik AM, et al. Transforming growth factor-beta initiates wound repair in rat liver through induction of the EⅢ A-fibronectin splice isoform. Am J Pathol, 2000, 156:115-124.
  • 5Qi Z, Atsuchi N, Ooshima A, et al. Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat. Proc Natl Acad Sci USA, 1999,96:2345-2349.
  • 6Nakamura T, Sakata R, Ueno T, et al. Inhibition of transforminggrowth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine-treated rats.Hepatology, 2000,32: 247-255.
  • 7Ueno H, Sakamoto T, Nakamura T, et al. A soluble transforminggrowth factor beta receptor expressed in muscle prevents liver fibrogenesis and dysfunction in rats. Hum Geno Ther, 2000,11: 33-42.
  • 8Nakamura T, Sakata R, Ueno T, et al. Inhibition of transforminggrowth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine-treated rats.Hepatology, 2000,32: 247-255.
  • 9Miyazono K. Signal transduction by bone morphogenetic protein receptors: functional roles of Smad proteins. Bone, 1999,25: 91-93.
  • 10Dooley S, Streckert M, Delvoux B, et al. Expression of Smadsduring in vitro transdifferentiation of hepatic stellate cells to myofibroblasts. Biochem Biophys Res Commun,2001,283:554-562.

共引文献12

同被引文献13

  • 1Friedman SL, Roll FJ. Isolation and culture of hepatic lipocytes, kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with stractan. Anal Biolchem, 1987 ,161:207-218.
  • 2Reeves HL, Friedman SL. Activation of hepatic stellate cellsa key issue in liver fibrosis. Front Biosci, 2002,7:D808-D826.
  • 3Park PH, Nan JX, Park EJ, et al. Effect of tetrandrine on experimental hepatic fibrosis induced by bile duct ligation and scission in rats. Pharmacol Toxicol, 2000,87: 261-268.
  • 4Gressner AM, Weiskirchen R, Breitkopf K, et al. Roles of TGF-beta in hepatic fibrosis. Front Biosci, 2002, 7: D793-D807.
  • 5Attisano L, Wrana JL. Signal transduction by the TGF-beta superfamily. Science, 2002, 296:1646-1647.
  • 6Nakao A, Afrakhte M, Moren A, et al. Identification of Smad7, a TGFbeta- inducible antagonist of TGF-beta signal-ling. Nature,1997, 389:631-635.
  • 7Dooley S, Streckert M, Delvoux B, et al. Expression of Smads during in vitro transdifferentiation of hepatic stellate cells to myofibroblasts. Biochem Biophys Res Commun,2001,283: 554-562.
  • 8Dooley S, Hamzavi J, Breitkopf K, et al. Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats. Gastroenterology, 2003,125:178-191.
  • 9Isono M, Soda M, Inoue A, et al. Reverse transformation of hepatic myofibroblast-like cells by TGFbetal/LAP. Biochem Biophys Res Commun, 2003, 311:959-965.
  • 10Taniguchi H,Kato N,Otsuka M,et al.Hepatitis C virus core protein upregulates transforming growth factor-beta 1 transcription [J].Med Virol, 2004,72( 1 ) : 52-59.

引证文献2

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部